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Patients today are living well into advanced age, and with multiple chronic illnesses. Just as there are aspects of oral health that impact systemic health, the same is also true. However, sometimes it can become overwhelming to recall all of the biomedical science knowledge you learned once upon a time. In this presentation, we will review how to stratify patients based on a medical risk assessment. We will then delve more deeply into medical conditions that may impact bleeding, wound healing, and risk of infection.